| 110* | TA Wood | Derbyshire v Leicestershire | 2023 | tt12403 |
| 104 | TWM Latham | Warwickshire v Derbyshire | 2025 | tt15513 |
| 101 | Shahid Afridi | Hampshire v Derbyshire | 2017 | tt6448 |
| 100 | LS Livingstone | Lancashire v Derbyshire | 2018 | tt7011 |
| 100* | WL Madsen | Derbyshire v Durham | 2022 | tt11072 |