| 1 | 255 | MA Roseberry & S Hutton | Durham v Herefordshire | 1995 | a9298 |
| 2 | 211* | G Clark & SG Borthwick | Durham v Hampshire | 2021 | a28520 |
| 3 | 221 | A Habib & VJ Wells | Leicestershire v Durham | 1997 | a10486 |
| 4 | 208 | CT Bancroft & MJ Richardson | Durham v Northamptonshire | 2019 | a27267 |
| 5 | 186* | MW Goodwin & GW Flower | Zimbabwe v West Indies | 2000 | a12857 |
| 6 | 175 | JEC Franklin & SJ Adshead | Gloucestershire v Durham | 2009 | a19822 |
| 7 | 110 | AZ Lees & BA Raine | Durham v Warwickshire | 2025 | a31862 |
| 8 | 99 | AC Voges & PJ Franks | Nottinghamshire v Durham | 2012 | a21996 |
| 9 | 66 | TT Bresnan & A Shahzad | Yorkshire v Durham | 2008 | a18951 |
| 10 | 81 | LE Plunkett & SJ Harmison | Durham v Somerset | 2008 | a19078 |