| 6-43 | DJ Bravo | West Indies v Zimbabwe | 2012/13 | o3339 |
| 5-46 | CH Gayle | West Indies v Australia | 2002/03 | o2021 |
| 5-85 | AU Rashid | England v West Indies | 2018/19 | o4099 |
| 4-19 | NW Bracken | Australia v Sri Lanka | 2006/07 | o2573 |
| 4-19 | M Muralitharan | Sri Lanka v Ireland | 2006/07 | o2575 |
| 4-25 | MF Maharoof | Sri Lanka v Ireland | 2006/07 | o2575 |
| 4-29 | GB Hogg | Australia v New Zealand | 2006/07 | o2577 |
| 4-32 | DJ Bravo | West Indies v Bangladesh | 2014 | o3509 |
| 4-36 | HR Walsh | West Indies v Ireland | 2019/20 | o4230 |
| 4-38 | AA Donald | South Africa v West Indies | 2000/01 | o1715 |
| 4-51 | Al-Amin Hossain | Bangladesh v West Indies | 2014 | o3509 |
| 4-60 | MA Wood | England v West Indies | 2018/19 | o4099 |