| 286 | JP Crawley | England A v Eastern Province | 1993/94 | f40829 |
| 284 | EAB Rowan | Eastern Province v Griqualand West | 1945/46 | f17013 |
| 241 | AG Puttick | Cape Cobras v Warriors | 2013/14 | f55195 |
| 217* | JD Nel | Western Province v Eastern Province | 1952/53 | f19861 |
| 214 | PG Amm | Eastern Province v Transvaal | 1988/89 | f38013 |
| 209* | RG Pollock | Eastern Province Invitation XI v International Cavaliers | 1962/63 | f24680 |
| 206* | AJ Clarke | Border v Eastern Province | 1925/26 | f11444 |
| 205 | A Tayfield | Transvaal v Eastern Province | 1961/62 | f24112 |
| 202 | L Hutton | Marylebone Cricket Club v Eastern Province | 1938/39 | f16411 |
| 202* | LJ Koen | Eastern Province v Boland | 1995/96 | f42085 |
| 202* | DL Haynes | Western Province v Eastern Province | 1996/97 | f42831 |
| 201* | SJ Cook | Transvaal v Eastern Province | 1982/83 | f34563 |
| 201 | M de Villiers | Eastern Province v Free State | 2024/25 | f62873 |