| 300 | DCS Compton | Marylebone Cricket Club v North Eastern Transvaal | 1948/49 | f18169 |
| 273 | CB Britz | Easterns v Limpopo | 2025/26 | f63089 |
| 244* | HG Kuhn | Titans v Lions | 2014/15 | f56089 |
| 236* | M van Jaarsveld | Titans v Western Province Boland | 2004/05 | f48169 |
| 234 | MN Erlank | KwaZulu-Natal Inland v Easterns | 2024/25 | f62529 |
| 217 | TG Mokoena | Easterns v Eastern Province | 2015/16 | f56576 |
| 217* | NJ van den Bergh | Lions v Titans | 2018/19 | f59251 |
| 212 | AJ Pienaar | Knights v Titans | 2010/11 | f53125 |
| 210 | RS Second | Knights v Titans | 2012/13 | f54505 |
| 208 | D Wiese | Easterns v Griqualand West | 2008/09 | f50982 |
| 208* | D Elgar | Titans v Cape Cobras | 2014/15 | f56314 |
| 207* | J Booysen | Easterns v Northerns | 2007/08 | f50616 |
| 205* | RE van der Merwe | Titans v Warriors | 2014/15 | f55779 |
| 202* | OA Ramela | Cape Cobras v Titans | 2014/15 | f56314 |